乙卯研究所 論文目録 (1968年〜)
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Res. Fdn. ITSUU Lab. Paper List (1968 or later)
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2011
- Retinoic Acid Receptor Antagonist LE540 Attenuates Wakefulness via the Dopamine D1 Receptor in Mice.
K. Kitaoka, M. Shimizu, N. Shimizu, S. Chikahisa, M. Nakagomi, K. Shudo, K. Yoshizaki, and H. Séi, Brain Res., 1423, 10-16 (2011).
- Diphenylamine-based Retinoid Antagonists: Regulation of RAR and RXR Function Depending on the N-substituent.
K. Ohta, E. Kawachi, H. Fukasawa, K. Shudo, and H. Kagechika, Bioorg. Med. Chem., 19(8), 2501-2507 (2011).
- Midbrain Dopaminergic Neurons Utilize Nitric Oxide/cyclic GMP Signaling to Recruit ERK that Links Retinoic Acid Receptor Stimulation to Up-regulation of BDNF.
Y. Kurauchi, A. Hisatsune, Y. Isohama, T. Sawa, T. Akaike, K. Shudo, and H. Katsuki, J. Neurochem., 116(3), 323-333 (2011).
- A Retinoic Acid Receptor Agonist Am80 Rescues Neurons, Attenuates Inflammatory Reactions, and Improves Behavioral Recovery after Intracerebral Hemorrhage in Mice.
H. Matsushita, M. Hijioka, A. Hisatsune, Y. Isohama, K. Shudo, and H. Katsuki, J. Cereb. Blood Flow Metab., 31(1), 222-234 (2011).
2010
- Synthesis and Application of [1,2,5]Triazepane and [1,2,5]Oxadiazepane as Versatile Structural Units for Drug Discovery.
H. Suzuki, I. Utsunomiya, and K. Shudo, Chem. Pharm. Bull., 58(7), 1001-1002 (2010).
- Novel Synthesis of Ureas: Application of t-Butylureas.
A. Ito, H. Muratake, and K. Shudo, Chem. Pharm. Bull., 58(1), 82-86 (2010).
2009
- Disposition of a New Tamibarotene Prodrug in Mice.
M. Sugitani, R. Abe, N. Ikarashi, K. Ito, H. Muratake, K. Shudo, and K. Sugiyama, Biol. Pharm. Bull., 32(12), 1997-2001 (2009).
- Synthetic Retinoid AM80 Inhibits Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis.
C. Klemann, B. J.E. Raveney, A. K. Klemann, T. Ozawa, S. von Hörsten, K. Shudo, S. Oki, and T. Yamamura, Am. J. Pathol., 174(6), 2234-2245 (2009).
- Oral Administration of Synthetic Retinoid Am80 (Tamibarotene) Decreases Brain β-Amyloid Peptides in APP23 Mice.
K. Kawahara, K. Nishi, M. Suenobu, H. Ohtsuka, A. Maeda, K. Nagatomo, A. Kuniyasu, M. Staufenbiel, M. Nakagomi, K. Shudo, and H. Nakayama, Biol. Pharm. Bull., 32(7), 1307-1309 (2009).
- Retinoic Acid Receptor Stimulation Protects Midbrain Dopaminergic Neurons from Inflammatory Degeneration via BDNF-mediated Signaling.
H. Katsuki, E. Kurimoto, S. Takemori, Y. Kurauchi, A. Hisatsune, Y. Isohama, Y. Izumi, T. Kume, K. Shudo, and A. Akaike, J. Neurochem., 110(2), 707-718 (2009).
- Encapsulation of the Synthetic Retinoids Am80 and LE540 into Polymeric Micelles and the Retinoids' Release Control
T. Satoh, Y. Higuchi, S. Kawakami, M. Hashida, H. Kagechika, K. Shudo, and M. Yokoyama, J. Control. Release, 136(3), 187-195 (2009).
- On the Structure of “5-Nitrosotropolone”.
A. Ito, H. Muratake, and K. Shudo, J. Org. Chem., 74(3), 1275-1281 (2009).
- Towards Retinoid Therapy for Alzheimer’s Disease.
K. Shudo, H. Fukasawa, M. Nakagomi, and N. Yamagata, Curr Alzheimer Res, 6(3), 302-311 (2009).
- The Effect of Am-80, a Synthetic Retinoid, on Spinal Cord Injury-Induced Motor Dysfunction in Rats.
M. Takenaga, Y. Ohta, Y. Tokura, A. Hamaguchi, K. Shudo, H. Okano, and R. Igarashi, Biol. Pharm. Bull., 32(2), 225-231 (2009).
- Oral Administration of Synthetic Retinoid Am80 Inhibits the Development of Type 1 Diabetes in Non-obese Diabetic (NOD) Mice.
M. Ishido and K. Shudo, Biol. Pharm. Bull., 32(1), 157-159 (2009).
- The Transcription Factors Nur77 and Retinoid X Receptors Participate in Amphetamine-induced Locomotor Activities.
E. Bourhis, J. Maheux, B. Paquet, H. Kagechika, K. Shudo, P. P. Rompré, C. Rouillard, and D. Lévesque, Psychopharmacology (Berl), 202(4), 635-648 (2009).
2008
- The RXR Agonists PA024 and HX630 Have Different Abilities to Activate LXR/RXR and to Induce ABCA1 Expression in Macrophage Cell Lines.
T. Nishimaki-Mogami, N. Tamehiro, Y. Sato, K. Okuhira, K. Sai, H. Kagechika, K. Shudo, S. Abe-Dohmae, S. Yokoyama, Y. Ohno, K. Inoue, and J. Sawada, Biochem. Pharmacol., 76(8), 1006-1013 (2008).
2007
- β-Cryptoxanthin, a Novel Natural RAR Ligand, Induces ATP-binding Cassette Transporters in Macrophages.
A. Matsumoto, H. Mizukami, S. Mizuno, K. Umegaki, J. Nishikawa, K. Shudo, H. Kagechika, and M. Inoue, Biochem. Pharmacol., 74(2), 256-264 (2007).
- タミバロテン (Tamibarotene).
首藤紘一 (K. Shudo), 化学療法の領域 (ANTIBIOTICS & CHEMOTHERAPY), 23(4), 95-99(609-613) (2007).
2006
- Synthetic Retinoid Am80 Reduces Scavenger Receptor Expression and Atherosclerosis in Mice by Inhibiting IL-6.
N. Takeda, I. Manabe, T. Shindo, H. Iwata, S. Iimuro, H. Kagechika, K. Shudo, and R. Nagai, Arterioscler. Thromb. Vasc. Biol., 26(5), 1177-1183 (2006).
- 【総説】レチノイドによる自己免疫疾患の治療 (Retinoid Therapy for Autoimmune Diseases).
深澤弘志 (H. Fukasawa), 影近弘之 (H. Kagechika), 首藤紘一 (K. Shudo), 日本臨床免疫学会会誌 (Jpn. J. Clin. Immunol.), 29(3), 114-126 (2006).
- A New RXR Agonist, HX630, Suppresses Intimal Hyperplasia in a Mouse Blood Flow Cessation Model.
G. Haraguchi, J. Suzuki, H. Kosuge, M. Ogawa, N. Koga, S. Muto, A. Itai, H. Kagechika, K. Shudo, and M. Isobe, J. Mol. Cell. Cardiol., 41(5), 885-892 (2006).
- Synthetic Study of Hetisine-type Aconite Alkaloids. Part 1: Preparation of Tetracyclic Intermediate Containing the C14-C20 Bond.
H. Muratake and M. Natsume, Tetrahedron, 62(29), 7056-7070 (2006).
- Synthetic Study of Hetisine-type Aconite Alkaloids. Part 2: Preparation of Hexacyclic Compound Lacking the C-Ring of the Hetisan Skeleton.
H. Muratake and M. Natsume, Tetrahedron, 62(29), 7071-7092 (2006).
- Synthetic Study of Hetisine-type Aconite Alkaloids. Part 3: Total Synthesis of (±)-Nominine.
H. Muratake, M. Natsume, and H. Nakai, Tetrahedron, 62(29), 7093-7112 (2006).
- 【総説】Hetisan型アルカロイドの合成研究 (±)-Nominineの全合成 (Synthetic Studies of Hetisan-Type Aconite Alkaloids Total Synthesis of (±)-Nominine).
村竹英昭 (H. Muratake), 有機合成化学協会誌 (J. Synth. Org. Chem. Jpn.), 64(3), 237-250 (2006).
2005
- Synthetic Retinoids: Recent Developments Concerning Structure and Clinical Utility.
H. Kagechika and K. Shudo, J. Med. Chem., 48(19), 5875-5883 (2005).
- Synthetic Retinoid Am80 Suppresses Smooth Muscle Phenotypic Modulation and In-Stent Neointima Formation by Inhibiting KLF5.
K. Fujiu, I. Manabe, A. Ishihara, Y. Oishi, H. Iwata, G. Nishimura, T. Shindo, K. Maemura, H. Kagechika, K. Shudo, and R. Nagai, Circ. Res., 97, 1132-1141 (2005).
- RXR Agonist Enhances the Differentiation of Cardiomyocytes Derived from Embryonic Stem Cells in Serum-free Conditions.
M. Honda, T. S. Hamazaki, S. Komazaki, H. Kagechika, K. Shudo, and M. Asashima, Biochem. Biophys. Res. Commun., 333(4), 1334-1340 (2005).
- HX531, a Retinoid X Receptor Antagonist, Inhibited the 9-Cis Retinoic Acid-induced Binding with Steroid Receptor Coactivator-1 as Detected by Surface Plasmon Resonance.
T. Kanayasu-Toyoda, T. Fujino, T. Oshizawa, T. Suzuki, T. Nishimaki-Mogami, Y. Sato, J. Sawada, K. Inoue, K. Shudo, Y. Ohno, and T. Yamaguchi, J. Steroid Biochem. Mol. Biol., 94(4), 303-309 (2005).
- Antimyeloma Effects of a Novel Synthetic Retinoid Am80 (Tamibarotene) through Inhibition of Angiogenesis.
T. Sanda, T. Kuwano, S. Nakao, S. Iida, T. Ishida, H. Komatsu, K. Shudo, M. Kuwano, M. Ono, and R. Ueda, Leukemia., 19(6), 901-909 (2005).
2004
- Modifying Effects of 1'-Acetoxychavicol Acetate (ACA) and the Novel Synthetic Retinoids Re-80, Am-580 and Am-55P in a Two-stage Carcinogenesis Model in Female Rats.
S. Orita, M. Hirose, S. Takahashi, K. Imaida, N. Ito, K. Shudo, H. Ohigashi, A. Murakami, and T. Shirai, Toxicol. Pathol., 32(2), 250-257 (2004).
- A Synthetic Retinoid Am80 (Tamibarotene) Rescues the Memory Deficit Caused by Scopolamine in a Passive Avoidance Paradigm.
K. Shudo, H. Kagechika, N. Yamazaki, M. Igarashi, and C. Tateda, Biol. Pharm. Bull., 27(11), 1887-1889 (2004).
- Differential Modulation of PI3-kinase/Akt Pathway During All-trans Retinoic Acid- and Am80-induced HL-60 Cell Differentiation Revealed by DNA Microarray Analysis.
S. Ishida, Y. Shigemoto-Mogami, Y. Shinozaki, H. Kagechika, K. Shudo, S. Ozawa, J. Sawada, Y. Ohno, and K. Inoue, Biochem. Pharmacol., 68(11), 2177-2186 (2004).
- Palladium-Catalyzed Intramolecular α-Arylation of Aliphatic Ketone, Formyl, and Nitro Groups.
H. Muratake, M. Natsume, and H. Nakai, Tetrahedron, 60(51), 11783-11803 (2004).
- Total Synthesis of (±)-Nominine, a Heptacyclic Hetisine-Type Aconite Alkaloid.
H. Muratake and M. Natsume, Angew. Chem. Int. Ed., 43(35), 4646-4649 (2004).
2003
- In Vitro Farnesoid X Receptor Ligand Sensor Assay Using Surface Plasmon Resonance and Based on Ligand-induced Coactivator Association.
T. Fujino, Y. Sato, M. Une, T. Kanayasu-Toyoda, T. Yamaguchi, K. Shudo, K. Inoue, and T. Nishimaki-Mogami, J. Steroid. Biochem. Mol. BiolLett., 87(4-5), 247-252 (2003).
2002
2000
1999
1998
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 15. Asymmetric Synthesis of (+)-Duocarmycin SA Using Novel Procedure for Preparation of Hydroxyindoles.
H. Muratake, N. Matsumura, and M. Natsume, Chem. Pharm. Bull., 46(4), 559-571 (1998).
- Synthesis of Duocarmycin SA by way of Methyl 4-(Methoxycarbonyl)-oxy-3H-pyrrolo[3,2-f]-quinoline-2-carboxylate as a Tricyclic Heteroaromatic Intermediate.
H. Muratake, M. Tonegawa, and M. Natsume, Chem. Pharm. Bull., 46(3), 400-412 (1998).
1997
- Palladium-Catalyzed Intramolecular α-Arylation of Aliphatic Ketones.
H. Muratake and M. Natsume, Tetrahedron Lett., 38(43), 7581-7582 (1997).
- A Novel Phenol-Forming Reaction for Preparation of Benzene, Furan, and Thiophene Analogs of CC-1065/Duocarmycin Pharmacophores.
H. Muratake, A. Hayakawa, and M. Natsume, Tetrahedron Lett., 38(43), 7577-7580 (1997).
- Synthesis of Furan and Thiophene Analogs of Duocarmycin SA.
H. Muratake, K. Okabe, M. Takahashi, M. Tonegawa, and M. Natsume, Chem. Pharm. Bull., 45(5), 799-806 (1997).
1996
- Alternative Synthesis of Duocarmycin SA Using a Tetracyclic Heteroaromatic Intermediate Prepared by Palladium-Catalyzed Coupling Reactions.
H. Muratake, M. Tonegawa, and M. Natsume, Chem. Pharm. Bull., 44(8), 1631-1633 (1996).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 14. Synthesis of (±)-Duocarmycin SA, Natural (+)-Duocarmycin SA, and Non-natural (−)-Duocarmycin SA.
H. Muratake, I. Abe, and M. Natsume, Chem. Pharm. Bull., 44(1), 67-79 (1996).
1995
- Total Synthesis of Natural (+)-Duocarmycin SA.
H. Muratake, N. Matsumura, and M. Natsume, Chem. Pharm. Bull., 43(6), 1064-1066 (1995).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 13. Enantiospecific Synthesis of Mitosene Analogues Related to FR900482 and FR88979.
I. Utsunomiya, H. Muratake, and M. Natsume, Chem. Pharm. Bull., 43(1), 37-48 (1995).
1994
- Total Synthesis of Antitumor Antibiotic, (±)-Duocarmycin SA.
H. Muratake, I. Abe, and M. Natsume, Tetrahedron Lett., 35(16), 2573-2576 (1994).
- Total Synthesis of a Frog Poison, (±)-Epibatidine, a Potent Non-opioid Analgesic.
K. Okabe and M. Natsume, Chem. Pharm. Bull., 42(7), 1432-1436 (1994).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 12. Enantiospecific Synthesis of Hapalindole O.
M. Sakagami, H. Muratake, and M. Natsume, Chem. Pharm. Bull., 42(7), 1393-1398 (1994).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 11. Total Synthesis of (6R,8S)-Herbindole A, (6R,8S)-Herbindole B, (6R,8S)-Herbindole C, (6R,8S)-cis-Trikentrin A, (6R,8S)-cis-Trikentrin B,
(6R,8R)-trans-Trikentrin B, and (6R,8R)-iso-trans-Trikentrin B. Determination of the Absolute Structures of Natural Herbindoles and Trikentrins.
H. Muratake, A. Mikawa, T. Seino, and M. Natsume, Chem. Pharm. Bull., 42(4), 854-864 (1994).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 10. Synthesis of 4- and/or 5-Alkylated 1,6,7,8-Tetrahydrocyclopent[g]indoles, Model Compounds for Herbindole and Trikentrin Syntheses.
H. Muratake, A. Mikawa, T. Seino, and M. Natsume, Chem. Pharm. Bull., 42(4), 846-853 (1994).
1993
- Total Synthesis of (6R,8S)-cis-Trikentrin B, (6R,8R)-trans-Trikentrin B, and (6R,8R)-iso-trans-Trikentrin B.
Determination of the Absolute Structures of the Natural Trikentrins B.
H. Muratake, T. Seino, and M. Natsume, Tetrahedron Lett., 34(30), 4815-4818 (1993).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion. Part 9. Synthesis of (1aS,8bS)-1-tert-Butyloxycarbonyl-8-formyl-1,1a,2,8b-tetrahydroazirino [2',3':3,4]pyrrolo[1,2-a]indole. Model Study for the Enantiospecific Synthesis of Aziridinomitosenes.
I. Utsunomiya, M. Fuji, T. Sato, M. Natsume, Chem. Pharm. Bull., 41(5), 854-860 (1993).
1992
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 8. Improved Practical Synthesis of 4,4-Dialkoxy-1-(1-arylsulfonyl-3-pyrrolyl)-1-butanone and 4-(1-Arylsulfonyl-3-pyrrolyl)-4-oxobutanal, and a Novel Synthetic Procedure for 4-Alkoxyindole Derivatives.
I. Utsunomiya, H. Muratake, and M. Natsume, Chem. Pharm. Bull., 40(9), 2358-2361 (1992).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 7. Synthesis of (±)-and (S)-(−)-Pindolol.
M. Fuji, H. Muratake, M. Akiyama, and M. Natsume, Chem. Pharm. Bull., 40(9), 2353-2357 (1992).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 6. Synthetic Procedure for 4-, 5-, 6- or 7-Alkoxy- and Hydroxyindole Derivatives.
M. Fuji, H. Muratake, and M. Natsume, Chem. Pharm. Bull., 40(9), 2344-2352 (1992).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion, Part 5. Efficient Preparative Procedure for 4-Substituted Indole Derivatives.
M. Fuji, H. Muratake, and M. Natsume, Chem. Pharm. Bull., 40(9), 2338-2343 (1992).
- Total Synthesis of (+)-Herbindole A, (+)-Herbindole B, and (+)-Herbindole C. Determination of the absolute Configuration of the Natural Herbindoles.
H. Muratake, A. Mikawa, and M. Natsume, Tetrahedron Lett., 33(32), 4595-4598 (1992).
- Synthesis of (±)-Tetrahydropseudodistomin, a Hydrogenation Product of Antineoplastic Alkaloids, Pseudodistomins A and B.
I. Utsunomiya, M. Ogawa, and M. Natsume, Heterocycles, 33(1), 349-356 (1992).
1991
- Synthesis of Teleocidins A, B and Their Congeners. Part 3. Synthesis of Dihydroteleocidin B-4 (Dihydroteleocidin B), Teleocidin B-3 and Teleocidin B-4.
K. Okabe, H. Muratake, and M. Natsume, Tetrahedron, 47(40), 8559-8572 (1991).
- Synthesis of Teleocidins A, B and Their Congeners. Part 2. Synthesis of Lyngbyatoxin A (Teleocidin A-1), Teleocidin A-2, Pendolmycin, and (R,E)- and (S,E)-7-(3,7,11-Trimethyl-1,6,10-dodecatrien-3-yl)-(−)-indolactams V.
H. Muratake, K. Okabe, and M. Natsume, Tetrahedron, 47(40), 8545-8558 (1991).
- Synthesis of Teleocidins A, B and Their Congeners. Part 1. An Efficient Synthesis Method of N-(7-Alkyl-4-indolyl)-N-methyl-L-valine Esters, Essential Intermediates for Teleocidin Synthesis.
H. Muratake and M. Natsume, Tetrahedron, 47(40), 8535-8544 (1991).
- The Second Generation Synthesis of a Tumor Promoter Pendolmycin.
K. Okabe and M. Natsume, Tetrahedron, 47(36), 7615-7624 (1991).
- Pendolmycin, a New Tumor Promoter of the Teleocidin A Class on Skin of CD-1 Mice.
S. Nishiwaki, H. Fujiki, S. Yoshizawa, M. Suganuma, H. Furuya-Suguri, S. Okabe, M. Nakayasu, K. Okabe, H. Muratake, and M. Natsume, Jpn. J. Cancer Res., 82(7), 779-783 (1991).
1990
- Synthetic Studies of Marine Alkaloids Hapalindoles. Part 3. Total Synthesis of (±)-Hapalindoles H and U.
H. Muratake, H. Kumagami, and M. Natsume, Tetrahedron, 46(18), 6351-6360 (1990).
- Synthetic Studies of Marine Alkaloids Hapalindoles. Part 2. Lithium Aluminum Hydride Reduction of the Electron-Rich Carbon-Carbon Double Bond Conjugated with the Indole Nucleus.
H. Muratake and M. Natsume, Tetrahedron, 46(18), 6343-6350 (1990).
- Synthetic Studies of Marine Alkaloids Hapalindoles. Part 1. Total Synthesis of (±)-Hapalindoles J and M.
H. Muratake and M. Natsume, Tetrahedron, 46(18), 6331-6342 (1990).
- Total Synthesis of Indole Alkaloid Pendolmycin.
K. Okabe, H. Muratake, and M. Natsume, Tetrahedron, 46(15), 5113-5120 (1990).
- Synthesis of (±)- and (−)-cis-Trikentrin A, (±)- and (−)-trans-Trikentrin A, (±)-cis-Trikentrin B, (±)-trans-Trikentrin B, and (±)-iso-trans-Trikentrin B.
H. Muratake, M. Watanabe, K. Goto, and M. Natsume, Tetrahedron, 46(12), 4179-4192 (1990).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion. Part 4.
H. Muratake and M. Natsume, Heterocycles, 31(4), 691-700 (1990).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion. Part 3.
H. Muratake and M. Natsume, Heterocycles, 31(4), 683-690 (1990).
1989
- Determination of the Absolute Structures of cis-Trikentrin A and trans-Trikentrin A by Synthesis of Their Enantiomers.
H. Muratake and M. Natsume, Tetrahedron Lett., 30(42), 5771-5772 (1989).
- Total Synthesis of Marine Alkaloids (±)-Hapalindoles J and M.
H. Muratake and M. Natsume, Tetrahedron Lett., 30(14), 1815-1818 (1989).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion. Part 2.
H. Muratake and M. Natsume, Heterocycles, 29(4), 783-794 (1989).
- Preparation of Alkyl-Substituted Indoles in the Benzene Portion. Part 1.
H. Muratake and M. Natsume, Heterocycles, 29(4), 771-782 (1989).
- Synthesis of Optically Active Teleocidins B-3 and B-4.
K. Okabe, H. Muratake, and M. Natsume, Chem. Pharm. Bull., 37(2), 563-564 (1989).
1988
1987
1986
1985
- A New Synthetic Method for the Framework of Aspidosperma Alkaloids Using Singlet Oxygen Chemistry.
M. Natsume, I. Utsunomiya, K. Yamaguchi, and S. Sakai, Tetrahedron, 41(11), 2115-2123 (1985).
- Total Synthesis of (±)-α-Cyclopiazonic Acid.
H. Muratake and M. Natsume, Heterocycles, 23(5), 1111-1117 (1985).
- Synthesis of the Sedum Alkaloid Sedinine.
M. Ogawa and M. Natsume, Heterocycles, 23(4), 831-834 (1985).
1984
- Total Synthesis of (±)-Palustrine and Structure Revision.
M. Natsume and M. Ogawa, Chem. Pharm. Bull., 32(9), 3789-3791 (1984).
- A New Synthesis of (±)-Vindorosine.
M. Natsume and I. Utsunomiya, Chem. Pharm. Bull., 32(6), 2477-2479 (1984).
- Synthesis of a Compound Having a Palustrine Structure.
M. Natsume, M. Ogawa, I. Yoda, and M. Shiro, Chem. Pharm. Bull., 32(2), 812-814 (1984).
- Total Synthesis of (±)-Cannabisativine.
M. Ogawa, N. Kuriya, and M. Natsume, Tetrahedron Lett., 25(9), 969-972 (1984).
1983
1982
- Stable Conformation of 2,6-cis-Disubstituted 1-Acyl-1,2,3,6-tetrahydropyridines and Stereoselective Formation of Palustrine Side Chain.
M. Natsume and M. Ogawa, Chem. Pharm. Bull., 30(9), 3442-3445 (1982).
- Stereoselective Synthesis of (±)-18-Deoxypalustrine and (±)-Deoxy-13-epipalustrine.
M. Ogawa, J. Nakajima, and M. Natsume, Heterocycles, 19(7), 1247-1252 (1982).
- Stereoselective Synthesis of (±)-Deethylaspidospermidine.
M. Natsume and I. Utsunomiya, Heterocycles, 17(1), 111-115 (1982).
1981
- An Alternative Synthesis of (±)-Dihydrosetoclavine.
M. Natsume and H. Muratake, Heterocycles, 16(9), 1481-1486 (1981).
- Total Synthesis of Prosophylline.
M. Natsume and M. Ogawa, Heterocycles, 16(6), 973-977 (1981).
- Synthesis of an Intermediate to the Tetracyclic Ergot Alkaloids.
M. Natsume, H. Muratake, and Y. Kanda, Heterocycles, 16(6), 959-962 (1981).
- Total Syntheses of (±)-Chanoclavine I and (±)-Dihydrosetoclavine.
M. Natsume and H. Muratake, Heterocycles, 16(3), 375-379 (1981).
- A Facile Synthesis of a Nuphar Alkaloid, Nupharolutine.
M. Natsume and M. Ogawa, Heterocycles, 15(1), 237-240 (1981).
1980
- Total Synthesis of (±)-6,7-Secoagroclavine.
M. Natsume and H. Muratake, Heterocycles, 14(8), 1101-1105 (1980).
- Stereoselective Synthesis of dl-Prosafrinine and dl-Pseudocarpamic Acid.
M. Natsume and M. Ogawa, Heterocycles, 14(5), 615-618 (1980).
- A Stereoselective Synthesis of dl-3-Epiuleine.
M. Natsume and Y. Kitagawa, Tetrahedron Lett., 21(9), 839-840 (1980).
- Useful Intermediate for the Synthesis of Ergot Alkaloids.
M. Natsume and H. Muratake, Heterocycles, 14(4), 445-448 (1980).
- Stereoselective Synthesis of dl-Carpamic Acid and dl-Azimic Acid.
M. Natsume and M. Ogawa, Heterocycles, 14(2), 169-173 (1980).
1979
- A Carbon-Carbon Bond Formation Using an Endoperxide of N-Methoxycarbonylpyrrole and a Convenient Synthesis of 4-Alkylindoles.
M. Natsume and H. Muratake, Tetrahedron Lett., 20(36), 3477-3480 (1979).
- A Carbon-Carbon Bond Formation Using Endoperxides of 1,2-Dihydropyridines.
M. Natsume, Y. Sekine, M. Ogawa, H. Soyagimi, and Y. Kitagawa, Tetrahedron Lett., 20(36), 3473-3476 (1979).
1978
- Synthetic Study of Amino-sugars from Pyridines. V. Synthesis of 5-Amino-5-deoxypiperidinoses from the Singlet Oxygen Adduct of 1-Acyl-1,2-dihydropyridines. (2)
M. Natsume, M. Wada, and M. Ogawa, Chem. Pharm. Bull., 26(11), 3364-3372 (1978).
- A Novel N-Amination method and Its Application to the Preparation of N-Aminoheterocycles.
M. Somei, M. Matsubara, Y. Kanda, and M. Natsume, Chem. Pharm. Bull., 26(8), 2522-2534 (1978).
- Synthetic Study of Amino-sugars from Pyridines. IV. Synthesis of 5-Amino-5-deoxypyperidinoses from the Singlet Oxygen Adduct of 1-Acyl-1,2-dihydropyridines. (1).
M. Natsume, Y. Sekine, and H. Soyagimi, Chem. Pharm. Bull., 26(7), 2188-2197(1978).
1977
1976
1975
- The Chemistry of Indoles. IV. Preparation of Pyridazino[2,3-a]indoles and as-triazino[1,6-a]indoles.
M. Somei, M. Matsubara, and M. Natsume, Chem. Pharm. Bull., 23(11), 2891-2898 (1975).
- Synthetic Studies on Amino-sugars from Pyridines. I. Synthesis of 1-O-Methyl-N-benzoyl-dl-nojirimycin.
M. Natsume and M. Wada, Chem. Pharm. Bull., 23(11), 2567-2572 (1975).
1974
- The Chemistry of Indoles (1-Aminoindoles), III.
M. Somei and M. Natsume, Tetrahedron Lett., 15(41), 3605-3608 (1974).
- An Application of the Photocyclization Reaction of Schiff Bases to the Synthesis of a Phenanthridine Alkaloid.
T. Onaka, Y. Kanda, and M. Natsume, Tetrahedron Lett., 15(13), 1179-1180 (1974).
- 1-Aminoindoles.
M. Somei and M. Natsume, Tetrahedron Lett., 15(5), 461-462 (1974).
1973
- Photochemical Rearrangements for the Syntheses of 3-, 4-, and 6-Substituted Indoles.
M. Somei and M. Natsume, Tetrahedron Lett., 14(27), 2451-2454 (1973).
- Reduction of Quinoline and Isoquinoline with Sodium Hydride.
M. Natsume, S. Kumadaki, Y. Kanda, and K. Kiuchi, Tetrahedron Lett., 14(26), 2335-2338 (1973).
1972
- Synthesis of 3H-4,5-Dihydro-3-benzazepine Derivatives from Isoquinolines.
M. Natsume and M. Wada, Chem. Pharm. Bull., 20(8), 1836-1838 (1972).
- Formation of 3-Cyano-1,4-dihydroquinolines and Their Conversion to Indole Derivatives.
M. Natsume and I. Utsunomiya, Chem. Pharm. Bull., 20(7), 1595-1598 (1972).
- 1,1-Disubstituted 1,2,3,4-Tetrahydroisoquinoline Derivatives from Isoquinolines.
M. Natsume, S. Kumadaki, and K. Kiuchi, Chem. Pharm. Bull., 20(7), 1592-1595 (1972).
- The Reaction of 4-Cyanoisoquinolines with the Grignard Reagent and Carbaions.
M. Natsume and M. Wada, Chem. Pharm. Bull., 20(7), 1589-1592 (1972).
1971
- Photochemical Addition of Alcohol, Esters, Ethers, and Amides to the Aromatic N-Heterocycles.
M. Natsume and M. Wada, Tetrahedron Lett., 12(47), 4503-4506 (1971).
- Wittig Reaction of N-Sulfonyl lactam.
M. Natsume, M. Takahashi, K. Kiuchi, and H. Sugaya, Chem. Pharm. Bull., 19(12), 2648-2651 (1971).
- A Note on a New Synthesis of N-Methylmorphinans. II.
M. Natsume and S. Kumadaki, Itsuu Kenkyusho Nenpo, 16, 47-51 (1971).
- Free Radical Reactions of Aromatic Amine N-Oxides. III. Free Radical Arylation of Aromatic Amine N-Oxides.
M. Natsume, S. Kumadaki, and R. Tanabe, Itsuu Kenkyusho Nenpo, 16, 25-39 (1971).
1968
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